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The Laboratory of Pharmaceutical Nanotechnology (Demetzos Lab) belongs to the Section of Pharmaceutical Technology of the Department of Pharmacy of the School of Health Sciences, National and Kapodistrian University of Athens (UoA). It is oriented in the area of applied nanotechnology, especially targeted drug delivery nanosystems and colloidal nanocarriers for therapeutic purposes. The lab has been and continues to be a participant in many international, european and national research programs. It is also in close collaboration with scientists and academic partners from institutions all over the world, as well as with a number of industries, aiming to produce scientific evidence that will aid the development and approval of innovative nanoproducts. It is also an active member of many scientific societies. Its director is Professor Costas Demetzos.



Recent News







Costas N. Demetzos, Professor of Pharmaceutical Technology & Nano-Technology, Department of Pharmacy of the National & Kapodistrian University of Athens, was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology. The ceremony took place during the formal sitting on the 21th of December, 2018 in the Great ceremony hall of the Academy of Athens, after the unanimous decision of the Athens Academy Plenary. The President of the Academy of Athens, Academician Antonios Kounadis presented the award to the honored Professor.




PhD student Nikolaos Naziris was awarded 1st prize for his oral presentation entitled
"Linear Thermodynamic Behavior in Complex Chimeric Nanosystems",
N. Naziris, A. Skandalis, S. Pispas, C. Demetzos,
in the
8th Hellenic Conference of Thermal Analysis and Calorimetry of the
Hellenic Society of Thermal Analysis (HSTA)





Dr. Natassa Pippa was a participant in the Lindau Nobel Laureate Meetings 2018,
among 600 young scientists who had the opportunity to meet 39 Nobel Laureates.
Read about it in eKathimerini and Onassis Foundation.



Adapted from eKathimerini


Latest Publications

The self-assembly process of amphiphilic molecules into solvents results in different mesophases,
such as inverse cubic and hexagonal that both belong to the wider category of lyotropic liquid crystals.
The above mesophases can be further exploited upon the formation of liquid crystalline nanoparticles,
cubosomes and hexosomes respectively, which may be utilized as drug delivery nanosystems,
exhibiting major advantages. In the present study, published in the International Journal of Pharmaceutics,
liquid crystalline nanoparticles were prepared and evaluated in terms of morphology and physicochemical behavior.



The goal of this study is to examine the effect of the different formulation parameters, as well as
the effect of the different microenvironmental factors (temperature, ionic strength, pH, serum proteins presence)
on their behavior. The physicochemical behavior and the morphology of the systems were investigated
by X-Ray Diffraction (XRD), cryogenic-Transmission Electron Microscopy (cryo-TEM), fluorescence spectroscopy
and a gamut of light scattering techniques.